I FEEL MORE LIKE ME AGAIN

BECAUSE SAPHNELO HAS MY LUPUS MORE UNDER CONTROL

Discover the power of SAPHNELO to reduce disease activity.*

*When compared to other lupus medicines alone. Disease activity reduction at the end of treatment was statistically significant in 2 of the 3 studies. Results may vary.

SEE WHAT SAPHNELO CAN DO

WHAT COULD SAPHNELO DO FOR YOUR LUPUS?

When added to other lupus medicines, SAPHNELO:

  • Reduced lupus disease activity*
  • Reduced oral steroid use*,†

*Compared to other lupus medicines alone.

In some patients on an oral steroid dose of ≥10 mg per day at study start, the oral steroid dose was reduced to ≤7.5 mg per day. Talk to your doctor before stopping or changing any medications.

SAPHNELO Educational Brochure

SAPHNELO EDUCATIONAL BROCHURE

Download the educational brochure to learn how adding SAPHNELO could make a difference, how SAPHNELO works, and more!

TWO WAYS TO TAKE SAPHNELO

SAPHNELO can fit into your monthly or weekly routine. The intravenous (IV) infusion is administered by your healthcare team once a month in their office or at an infusion center, and takes 30 minutes. Self-injection with the SAPHNELO Pen or pre-filled syringe is for once-a-week use at home, or wherever you happen to be.

Explore both options and discuss with your doctor which SAPHNELO treatment may be right for you.

Real SAPHNELO Patients

SAPHNELO STORIES

Watch real patients talk about their inspiring lupus journeys, and their experiences after SAPHNELO was added to their treatment plan.

Individual experiences may vary.

Ask your doctor if adding SAPHNELO may be right for you.

SUPPORT FROM THE START

SAPHNELO Supports was designed in collaboration with real lupus patients to provide you with the support and resources you need to start and stay on treatment with SAPHNELO.

Most eligible patients pay as little as $0* for SAPHNELO through the SAPHNELO Supports co-pay savings program.

*See full Eligibility and Terms of Use.

Pay as little as

$

0

*

for SAPHNELO

*See full Eligibility and Terms of Use

RESOURCES FOR YOUR TREATMENT JOURNEY

Whether you are considering talking to your doctor about SAPHNELO or have already been prescribed SAPHNELO and are wondering what comes next, there are resources to guide and support you along the way.

DOCTOR DISCUSSION GUIDE

This discussion guide is designed to help you start a conversation with your doctor about your lupus treatment goals and whether adding SAPHNELO could be right for you.

CO-PAY SAVINGS BROCHURE

Learn how eligible patients can save on SAPHNELO through the SAPHNELO Supports Co-pay Savings Program.

SAPHNELO TIPS FOR SELF-INJECTION

A quick guide to confident injections with your SAPHNELO Pen. Learn about the SAPHNELO self-injection process and find tips on preparing for your first injection. This document can help you understand what you may expect before, during, and after SAPHNELO administration.

SAPHNELO TIPS FOR IV INFUSION

A quick guide to getting ready for your infusion. Learn about the SAPHNELO IV Infusion process and find tips on preparing for your first appointment. This document can help you understand what you may expect before, during, and after receiving SAPHNELO.

Todos los recursos también están disponibles en español.

LOOKING FOR AN INFUSION CENTER?

If you and your rheumatologist have decided that SAPHNELO is right for you, the National Infusion Center Association (NICA) is a public resource that may help you locate an infusion center. Check out this external resource to locate a center near you.

By completing this registration, I confirm that I am at least 18 years old, agree to receive information about SAPHNELO, and may receive information about other immunology medicines and services related to my condition which includes, but is not limited to, educational and promotional materials, special offers and services and for market research purposes, which includes contacting me to participate in focus groups, surveys or interviews. This may include AstraZeneca or a third party working on AstraZeneca's behalf contacting me by telephone, e-mail and text message regarding AstraZeneca Support Programs that may be of interest to me. Information provided by AstraZeneca does not take the place of talking to your healthcare provider about your treatment or condition. If you no longer want to receive health-related materials, call 1-800-236-9933. Please visit www.azprivacynotice.com to review our Privacy Notice.

By providing your phone number, you are opting in to receive updates and support messages from SAPHNELO. Text STOP to opt out. Text HELP for help. Message frequency will vary. Message and data rates may apply. For more information, visit Privacy Notice or Terms & Conditions.

IMPORTANT SAFETY INFORMATIONWhite CaratWhite Carat

  • Do not use SAPHNELO if you are allergic to anifrolumab-fnia or to any of the ingredients
  • Before you receive SAPHNELO, tell your healthcare provider about all of your medical conditions, including if you:
    •  Think you have an infection or have an infection that keeps coming back
    •  Are scheduled to receive a vaccination or if you think you may need a vaccination. You should not receive live vaccines during treatment with SAPHNELO
    •  Have or have had cancer
    •  Are receiving other biologic medicines or monoclonal antibodies
    •  Are pregnant or plan to become pregnant. It is not known if SAPHNELO will harm your unborn baby. Tell your healthcare provider if you are, might be, or plan to become pregnant during treatment with SAPHNELO
      • Pregnancy exposure registry monitors pregnancy outcomes in women exposed to SAPHNELO. You can find out more information about the registry by calling AstraZeneca at 1-877-693-9268
    •  Are breastfeeding or plan to breastfeed. It is not known if SAPHNELO passes into your breast milk

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. SAPHNELO may affect the way other medicines work, and other medicines may affect how SAPHNELO works.

SAPHNELO may cause serious side effects, including:

  • Serious infections: SAPHNELO can lower the ability of your immune system to fight infections. You may be at a higher risk of developing respiratory infections and shingles (herpes zoster) during treatment with SAPHNELO. Infections could be serious, leading to hospitalization or death. Tell your healthcare provider right away if you have any of the following symptoms of an infection:
    • fever, sweating, or chills
    • muscle aches
    • cough
    • shortness of breath
    • burning when urinating
    • urinating more often
    • diarrhea or stomach pain
    • warm, red, or painful skin or sores on your body
  • Allergic (hypersensitivity) reactions, including anaphylaxis: Serious allergic reactions can happen during or after SAPHNELO administration. Tell your healthcare provider or get emergency help right away if you have any of the following symptoms of a serious allergic reaction:
    •  swelling of your face, mouth, and tongue
    •  breathing problems
    •  fainting or dizziness
    •  feeling lightheaded (low blood pressure)
  • Cancer: SAPHNELO may reduce the activity of your immune system. Medicines that affect the immune system may increase your risk of certain cancers

The most common side effects of SAPHNELO include:

  •  Upper respiratory infections
  •  Bronchitis
  •  Infusion reactions (when given intravenously)
  •  Shingles (herpes zoster)
  •  Cough

These are not all the possible side effects of SAPHNELO. Call your healthcare provider for medical advice about side effects.

What is SAPHNELO?

SAPHNELO is a prescription medicine used to treat adults with moderate to severe systemic lupus erythematosus (SLE or lupus) who are receiving other lupus medicines.

It is not known if SAPHNELO is effective in patients with severe active lupus nephritis or severe active central nervous system lupus. It is not known if SAPHNELO is safe and effective in patients under 18 years of age.

IMPORTANT SAFETY INFORMATION

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